An Unregulated Market
Research chemicals sit outside the regulatory frameworks that govern pharmaceuticals. No agency verifies a purity claim before it goes on a label. A supplier can print "99% pure" on a vial containing 70% target peptide, 20% truncated sequences and 10% residual salts, and face no consequence unless a customer independently tests it.
That gap is why irreproducible results are so common in peptide research. When a compound fails to behave as the literature describes, the material is at least as likely to be the cause as the model.
If a supplier cannot show you a test result tied to your specific lot number, you do not know what you bought.
What we do differently
Every lot we release is tested by an independent ISO 17025 accredited laboratory before it enters inventory. We publish the resulting certificate against the lot number in our COA library, free to download without an account, and keep the record accessible indefinitely. We do not put paperwork in the box, and nothing is released against a generic or historical certificate.
Five Tests, Every Lot
Purity alone does not tell you whether you received the right compound. We run identity, purity, moisture, solvent and endotoxin because each answers a different question.
Reverse-phase HPLC
Separates the target peptide from truncated sequences, deletion products and synthesis by-products. Reported as area percent at 214 nm — the wavelength that detects the peptide bond itself rather than aromatic residues, so it does not flatter sequences that happen to contain tryptophan.
Mass spectrometry
Electrospray ionisation confirms the observed molecular weight matches the theoretical mass of the intended sequence. This is the test that proves identity. A 99% pure vial of the wrong peptide is still the wrong peptide.
Karl Fischer moisture
Lyophilised peptides are hygroscopic. Residual water drives hydrolysis in storage and means the mass in the vial is not all peptide. We report water content so you can calculate true net peptide when accuracy matters.
Residual solvent (GC)
Headspace gas chromatography quantifies TFA, acetonitrile and other synthesis and purification solvents. Residual TFA in particular is a known confounder in cell-culture work at low micromolar concentrations.
Endotoxin (LAL)
Limulus amebocyte lysate assay for bacterial endotoxin. Critical for any immune, inflammatory or cell-based model, where contaminating LPS produces exactly the kind of signal researchers are often looking for.
Net peptide content
The figure most suppliers omit. Gross vial mass includes counterions and water; net peptide content tells you how much actual peptide you have. Essential for accurate molar calculations.
From Synthesis To Your Bench
Synthesis & purification
Solid-phase synthesis, then preparative HPLC purification to the target specification. Crude material is never released.
Lot assignment
Each purified batch receives a unique lot number at the point of lyophilisation. That number follows the material for its entire life.
Independent testing
Samples are drawn and sent to an accredited third-party laboratory. We do not self-certify, and we do not accept the manufacturer's own paperwork as sufficient.
Release or reject
Lots below specification are rejected outright rather than downgraded or blended. Rejected material is not sold at a lower purity grade.
Publication
The certificate is published against the lot number in the COA library, accessible without an account.
Dispatch
Your vial ships with its lot number on the label. Look that number up in the COA library and check it agrees before you use the material.
Don't Take Our Word
We would rather you tested us than trusted us. If you have HPLC access, run our material and compare it to the certificate. If the numbers do not agree within reasonable analytical variance, contact us and we will replace the order and investigate the lot.
This is also the reason our sampler kits exist. Buying four 5 mg vials to qualify a supplier costs far less than discovering a purity problem halfway through a study.
What if my assay disagrees?
Send us your trace and the lot number. We re-pull the retention sample, re-test it independently, and publish an amendment if the original certificate was wrong. Full refund or replacement either way.
Do you keep retention samples?
Yes — a sealed retention sample from every lot is held so any released batch can be re-tested later against a dispute.
Is the testing lab named?
The accredited laboratory and its registration number appear on the certificate itself, so you can verify the accreditation independently.
Check A Batch Right Now
Search the public COA library by compound or lot number — no account required.